Clean room What is ? And in what cases is it used? Design and construction A clean room is a room where the concentration of particles in the air and the temperature, humidity and pressure must be controlled.. Also, it must be designed and constructed in such a way that the entry of particles and also if their survival is low. As it turns out, the room is clean or clean (cleanroom) Also, clean room equipment is one of the services Which the comprehensive think tank of Iranian industry has made and dealt with in a very specialized and strong way.What is the use of a clean room in sensitive industries and production lines such as : Electronic and Microelectronics Industries,Pharmaceutical industry, hospitals, food industry and … Is used.
Clean room equipment
Clean room products can be:
Clean room door (Clean Rome) , Clean room clothes, interlock dependent system,Making all kinds of clean room doors completely flashed And compatible with cGMP with aluminum frame and UPVC at a reasonable price and their interlock systems with easy installation Clean room hall (Clean Rome)،Clean room furniture ( Clean Rome) Air shower Air clean room ( Clean Rome ) Clean room air conditioner , Filter unit, weighing chamber, clean room windows, box, post trox, Shelf table, monitoring system, HEPA and ALPA filters, Air Shaver system, HEPA box filter,Flooring, pvc curtains, air showers, laminar hood,Channel ducting and filtering of steel equipment and … Cited.
The position of comprehensive thinkers of Iranian industry
The comprehensive industry think tank of Iranian industry has been very successful in validating and testing equipment. Comprehensive Factory of Iranian Industry Thinkers as the first company to be established in Iran with maximum sales and a large share of the Iranian market and sometimes abroad In the room industry Clean and its equipment and accessories with first-class quality and the comprehensive thinking of the Iranian industry First, it has become original and superior Is . Also, the company of comprehensive thinkers of Iranian industry is the first and first place in Expertise and product development consulting in Iran and Abroad. The reason for success and growing Factory of comprehensive thinkers of Iranian industry, 100% customer satisfaction as the main plans and Strategies of designers and managers Specialists in the company.
Andishegaran Comprehensive Iranian Industry Company(Aisha)
In what cases is a clean room used? Factories such as factories, pharmaceutical companies, health, medical equipment, food and chemical industries, and clean rooms are divided into three groups..
1- Clean room ( Dynamic ) In operation
2- Clean room (Static) ready to work
3-Clean room built or prefabricated
Dynamic clean room:
In these rooms, raw materials are purchased and production is done, and the personnel in the room are doing their work . And all the equipment, devices and systems, spaces have been installed And before installing the equipment, the amount of pollution in the room is measured. In this case, the analysis method is made in one room Used And ready-to-use or exploited conditions may be scalable, and it s best to use operating conditions to determine the classroom of a clean room to be used. Because the quality of work in this room is higher. And in the case of small rooms, it is difficult to create dynamic working conditions, which is why it is recommended In such rooms, static should be used to determine the class of the room And there are differences of opinion between the US Pharmacopoeia and the European GMP Law on the operation and operation of machinery and equipment, or they have not yet been used.. The clean room should be built in such a way that it has the least amount of pollution and dust. Places such as pharmaceuticals and semiconductor industries should have clean rooms. Design and construction of a clean room with the best quality clean room, usually in any industry where small and contaminated particles. There is an impact on lowering the quality of manufacturing products. Clean pharmacy room , Biotechnology, aerospace, power plants, military processes and the Ministry of Energy are among the places and jobs They need clean rooms. In the following, we will discuss more about the process of making and designing this functional room.
Clean room is static
To a space where all matters related to the installation of systems and spaces and production equipment have been completed. A clean room is called a stationary room, and this equipment and devices work without the presence of personnel.
Built room
In a room where the installation of equipment and spaces has been completed and all the equipment and tools have been produced, but still installation and commissioning
It is said that the construction of the room has not been completed and the staff has not been present in this room yet
EU system
This set of standards was set to increase the efficiency of GMP in sensitive industries. Human and animal medicinal products were very effective. This system is used under the name of the EU GMP Code.. Manufacturers must use a clean room for the production process and staff must wear special clothing.
And to achieve the desired level of cleanliness, air conditioners equipped with filters and with very high and high efficiency should be used in the clean room where the production process takes place with sterile conditions. Areas where the production process takes place should be separated from other areas by the same isolating spaces and walls from the same room intended for the filling process..
What does a cleanroom microbial test mean?
The microbial test of a clean room is done in three ways.
1- Settle plate Microbial control of clean room plating: In this method of standard plinths with a diameter 9 Cm is used in a fixed place
2-Contact plate Microbial control of clean room contact: In this method of standard plinths with a diameter 5.5 Is used.
3-Air sampling Device: In this method with the help of air sampling device with standard diameter plinths 9 Centimeters measure the number of microbes in the air per cubic meter.
What is a clean room?
A clean room is actually an enclosed space where particles, pollutants and pollutants in the air, They have very little limit. The ceiling and walls of the clean room are made of sandwich panels. Clean rooms have equipment that can control the volume of pollutants And if they exist, eliminate them by using this equipment in addition to reducing pollutants and contaminated particles, Humidity is also controlled. Clean room specifications according to the probability of existence Microbes and pollutants are determined per cubic meter of space.
Clean room design 4 There is a constitution:
Contaminants should not enter the controlled environment from the outside.
Devices in a controlled environment should not cause contamination.
Contaminants in the controlled environment should not be combined and accumulated.
Possible contamination should be eliminated as soon as possible.
Clean room standards
- Clean rooms and the equipment in them are made to high standards.
- The amount of particles and pollutants in the air is measured based on the size and volume of the particles per cubic meter of room..
- On the other hand, there is advanced equipment to meet these standards and eliminate these suspended particles.
Among the equipment that meets the standards of a clean room according to ISO are the following:
Steelroom cleanroom equipment
Channeling and fan filters
So box
Clean Room Clean Room Cleanroom
Bench clean rooms
Clean Room Window: Glass double glazed windows that are well insulated against sound and heat.
Clean Room Door: Clean Roman doors can be made of glass or aluminum. Aluminum doors have more applications.
For beautiful appearance features, high strength, good filtering, strong air strength, thermal insulation, maintaining proper and clean heat
They are easy to do.
Clean room table and hood
Airlock
Cabinets and cabinets clean rooms
Ventilation systems and clean room air filter
Clean room air conditioning in environments that require critical particle control, temperature, relative humidity, ventilation, noise, vibration and space pressure They have a very high user.
Below we have described the equipment related to air conditioning. In addition to designing and manufacturing industrial air conditioners for maintenance and overhaul of industrial air conditioners and hospitals and pharmaceutical factories, the Comprehensive Iranian Industrial Thinkers Company also provides special services..
Fan filters and fans: This is the main thing that filter fans do in a clean room
Which refresh the air flow and circulate it. Clean Rooms have classes with different classifications.
With the powerful filtration that fan filters have, it is possible to have classroom clean rooms And Created Powerful fan filters are two-motor, one of which is the centrifugal fan motor And it has the ability to control the heating and cooling of the air.
Airlock: Prior to airlock, air showers were used to remove polluted air. But the cost-effectiveness of the airlock made it a great alternative. Corridors and controlled environments are among the places in Clean Rome that benefit from the airlock. Airlock applications include air pressure control and elimination of airborne contaminants.
Application of pass boxes in Clean Room
Another helper for clean rooms is the pass boxes.
The use of post-boxes is more for transferring clean objects or devices from a non-polluting environment to another clean environment..
This is done more to prevent contamination of objects and equipment if there is a non-clean environment in the transmission path. Do not carry the transferred
So the boxes are made of stainless steel and have double-walled doors.
Inside the back boxes are ultraviolet lamps that have a very strong microbial ability..
Construction and design of clean rooms in Iran
Andishegaran Jameh Sanat Iranian Company is one of the top companies in the field of clean room construction. The company s activities are completely up-to-date and in line with current research and technology. Comprehensive thinkers, construction and design of a variety of clean rooms, including for pharmaceuticals, industrial occupations, microbiology and laboratories Do. The equipment used and the air purifiers in the construction of the clean room are very high quality and according to the last floor. ISO classifications are selected. You can order the construction of a clean room for comprehensive thinkers in the Iranian industry through the companys website or email and phone number. Register research and industry.
In the standard ISO 1-14644 method, a specific method has been determined:
– Size required for each sample
– Accepted ranges
– Number of sampling sitesClean room classification in the pharmaceutical industry
Clean room design and construction
In phase Clean room design Both basic design and detailed design (Detail Engineering) The company uses the latest software for design and simulation, which is used in the world. By simulating drug and food production plantations, design problems and weaknesses on paper are corrected. Modern world software such as CFD, Solid work and computational software facilities that three-dimensional models and calculations of the desired design of the project will be presented and made.
It is safe to say that Klein is Roman (clean room) An environment with controlled pollution of suspended particles in space, in which there is a certain number of particles per cubic meter.. It is commonly used for the production of semiconductor materials such as germanium, silicon or for the production of medical technological devices and other fields.. The air flow is directed inwards (clean room) They are filtered and filtered by special devices and indoor air Clean room environment (clean room) It is permanently rotated and refined. Employees also enter the changing rooms, and wear gloves, hats and special shoes…They use depending on the classification.
Clean room equipment and devices in Clean Room are designed to create the least number of airborne particles.. In terms of airflow, they are divided into two general categories: ۱- Clean room with laminar flow (Unidirectional) ۲- With non-laminar flow (Non-one-way) The choice of the type of Clean Room flow is done according to the desired flow and application. With Laminar flow, it provides a higher class, or in other words, a higher degree of cleanliness.
This type is used in industries sensitive to particle and microbial contamination. From Hygienic air conditioner It is used because of the need for clean air, which includes heating and cooling, humidification and dehumidification..
Hygienic air conditioner
The main equipment and system used in creating space and producing clean air in the ventilation industry. Hygienic air conditioner is structurally similar to conventional air conditioner, with the difference that the ability to filter and clean up to 99.99% is advanced and fully specialized. has it. Clean channel rooms and related facilities : Related channels and facilities The clean room of the comprehensive thinkers of Iranian industry Design, manufacture and implementation of all types of pre insulated ducts (Preinsulated) , Galvanized and steel. Pre-insulated channels of TD Australia, PAL and ALP . Channel tests based on US SMACNA standard Supply of filters, valves and diffusers in different types and sizes .
Design, construction and installation of industrial facilities including : Types of compressors, chillers, fans and systems. Plumbing related facilities and equipment, especially clean steam production line and injectable water used in pharmaceutical Industries Using ARC and Arbital welding technology (Orbital Welding). All installation systems, HVAC, Package Unit and engine room facilities.
